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细胞实验显示这两种CAR都能提高星形胶质细胞摄取Aβ的能力，Cre-Megf10更突出，Adu-Dectin1还能促进小胶质细胞吞噬；小鼠体内实验表明Adu-Dectin1可明显提升脑内星形胶质细胞对Aβ的摄取，两种CAR在AD模型小鼠脑中能稳定表达较长时间，阳性细胞会聚集在淀粉样斑块周围，这些结果说明Cre-Megf10和Adu-Dectin1这两种CAR疗法值得进一步开展更大规模的体内研究。
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DNA is a polymer, composed of monomeric units called nucleotides. Each nucleotide is composed of ribose (a five carbon sugar) on which are attached a phosphate group as well as one of four nucleobases: Adenine (A), Cytosine (C), Guanine (G) of Thymine (T). These four types of nucleotide monomers link up with one-another, through phosphate-sugar bonds, creating a single strand of DNA. The ordered sequence of these four types of nucleotides in strand encodes all the genetic information necessary for the organism to function. Nucleotides in a strand form strong complementary bonds with nucleotides from another strand, A with T and C with G. These bonds allow two strands of DNA to form the double-helix structure of DNA1 shown in Figure 1.1. The specificity of nucleotide bonds ensure that the two strands of the double helix are complementary and that the information contained in one strand can be recovered from the other. This ensures a certain structural stability to the DNA molecule and a way to recover the important information that could be lost due to a damaged strand.。业内人士推荐传奇私服新开网｜热血传奇SF发布站｜传奇私服网站作为进阶阅读
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